Anti-COL3A1 antibody

Rs. 50,211.00
SKU stj92388

General Information

Product name Anti-COL3A1 antibody
Short Description Rabbit polyclonal to COL3A1.
Description COL3A1 is a protein encoded by the COL3A1 gene which is approximately 138,5 kDa. COL3A1 is secreted into the extracellular space and matrix. It is involved in collagen chain trimerization, integrin pathway, ERK signalling, phospholipase-C pathway and binding and uptake of ligands by scavenger receptors. It is involved in regulation of cortical development and is a major ligand of ADGRG1 in the developing brain. COL3A1 is expressed in skin, pancreas, bone, liver and lung. Mutations in the COL3A1 gene result in Ehlers-Danlos syndrome and thoracic aortic aneurysms. stj92388 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of COL3A1 protein.
Applications IHC,IF,ELISA,ICC
Dilution range IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000
Protein Name Anti-COL3A1 antibody
Immunogen Synthesized peptide derived from human COL3A1
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 95 kDa
Database Links
Alternative Names Collagen alpha-1 antibody
III chain antibody
Function Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
Cellular Localization Secreted, extracellular space, extracellular matrix
Tissue Specificity
Swiss-Prot Key

 

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