Anti-CPEB1 Antibody

Rs. 45,619.00
SKU stj27709

General Information

Product name Anti-CPEB1 Antibody
Short Description Rabbit polyclonal to CPEB1
Description This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CPEB1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 282-561 of human CPEB1 (NP_085097.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 62.6 kDa
Database Links
Alternative Names CPEB1Cytoplasmic polyadenylation element-binding protein 1 antibodyCPE-BP1 antibodyCPE-binding protein 1 antibodyh-CPEB antibodyhCPEB-1CPEB1 antibodyCPEB
Function Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons, Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR, RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism.
Cellular Localization Cytoplasm.
Tissue Specificity Isoform 1 is expressed in immature oocytes, ovary, brain and heart, isoform 2 is expressed in brain and heart, isoform 3 and isoform 4 are expressed in brain, expressed in breast tumors and several tumor cell lines.
Swiss-Prot Key

 

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