Anti-CRCP Antibody

Rs. 45,619.00
SKU stj116253

General Information

Product name Anti-CRCP Antibody
Short Description Rabbit polyclonal to CRCP
Description This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name DNA-directed RNA polymerase III subunit RPC9RNA polymerase III subunit C9Calcitonin gene-related peptide-receptor component proteinCGRP-RCPCGRP-receptor component proteinCGRPRCPHsC17
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human CRCP (NP_001035737.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 16.9 kDa
Database Links
Alternative Names CRCPDNA-directed RNA polymerase III subunit RPC9 antibodyRNA polymerase III subunit C9 antibodyCalcitonin gene-related peptide-receptor component protein antibodyCGRP-RCP antibodyCGRP-receptor component protein antibodyCGRPRCP antibodyHsC17CRCP
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs, Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses, Acts as nuclear and cytosolic DNA sensor involved in innate immune response, Can sense non-self dsDNA that serves as template for transcription into dsRNA, The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Cellular Localization Nucleus
Tissue Specificity Ubiquitous, most prevalent in testis.
Swiss-Prot Key

 

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