Anti-CREB3 Antibody

Rs. 45,619.00
SKU stj28650

General Information

Product name Anti-CREB3 Antibody
Short Description Rabbit polyclonal to CREB3
Description This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:10 - 1:100
Protein Name Anti-CREB3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human CREB3 (NP_006359.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 41.4 kDa
Database Links
Alternative Names CREB3Cyclic AMP-responsive element-binding protein 3 antibodyCREB-3 antibodycAMP-responsive element-binding protein 3 antibodyLeucine zipper protein antibodyLuman antibodyTranscription factor LZIP-alphaCREB3 antibodyLZIP
Function Endoplasmic reticulum (ER)-bound sequence-specific transcription factor that directly binds DNA and activates transcription Processed cyclic AMP-responsive element-binding protein 3: It's transcriptional activity is inhibited by CREBZF in a HCFC1-dependent manner, by the viral transactivator HCV core protein.
Cellular Localization Endoplasmic reticulum membrane, Cytoplasm.
Tissue Specificity Ubiquitously expressed.
Swiss-Prot Key

 

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