Anti-CRHR1 Antibody

Rs. 68,577.00
SKU stj71060

General Information

Product name Anti-CRHR1 Antibody
Short Description Goat polyclonal to CRHR1
Description
Applications ELISA, IHC
Dilution range
Protein Name Anti-CRHR1 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 50.7 kDa
Database Links
Alternative Names CRHR1Corticotropin-releasing factor receptor 1 antibodyCRF-R-1 antibodyCRF-R1 antibodyCRFR-1 antibodyCorticotropin-releasing hormone receptor 1 antibodyCRH-R-1 antibodyCRH-R1CRHR1 antibodyCRFR antibodyCRFR1 antibodyCRHR
Function G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin), Has high affinity for CRH and UCN, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase, Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels, Inhibits the activity of the calcium channel CACNA1H, Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress, Plays a role in the response to anxiogenic stimuli,
Cellular Localization Cell membrane
Tissue Specificity Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe,
Swiss-Prot Key

 

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