Anti-CRIF1 antibody

Rs. 50,211.00
SKU stj92476

General Information

Product name Anti-CRIF1 antibody
Short Description
Description Rabbit polyclonal to CRIF1.
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:40000
Protein Name Anti-CRIF1 antibody
Immunogen Synthesized peptide derived from human CRIF1
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 25.384 kDa
Database Links
Alternative Names Growth arrest and DNA damage-inducible proteins-interacting protein 1 antibody
39S ribosomal protein L59, mitochondrial antibody
MRP-L59 antibody
CKII beta-associating protein antibody
CR6-interacting factor 1 antibody
Mitochondrial large ribosomal subunit protein mL64 antibody
Papillomavirus L2-interacting nuclear protein 1 antibody
PLINP antibody
PLINP-1 antibody
p53-responsive gene 6 protein antibody
MRPL59 antibody
PLINP1 antibody
PRG6 antibody
Function Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Cellular Localization Mitochondrion Nucleus. Using N-terminally tagged constructs, has been found in the nucleus . C-terminally tagged constructs are targeted exclusively to mitochondria . This discrepancy may be explained by masking of a potential N-terminal mitochondrial targeting signal by the tag .
Tissue Specificity Widely expressed. Highly expressed in the thyroid gland, heart, lymph nodes, trachea and adrenal tissues. Expressed at lower level in liver skeletal muscle, kidney, pancreas, testis, ovary and stomach. Barely detectable in adrenal adenoma and papillary thyroid cancer.
Swiss-Prot Key

 

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