General Information
| Product name | Anti-CRP antibody |
|---|---|
| Short Description | Mouse monoclonal to CRP |
| Description | CRP is a member of the class of acute-phase reactants, as its levels rise dramatically during inflammatory processes occurring in the body. CRP rises up to 50,000-fold in acute inflammation, such as infection. It rises above normal limits within 6 hours, and peaks at 48 hours. Its half-life is constant, and therefore its level is mainly determined by the rate of production (and hence the severity of the precipitating cause). CRP is used mainly as a marker of inflammation. Measuring and charting CRP values can prove useful in determining disease progress or the effectiveness of treatments. |
| Applications | ELISA |
| Dilution range | |
| Protein Name | Anti-CRP antibody |
| Immunogen | human C-reactive protein (CRP), binding is Ca2+ independent |
| Storage Instruction | 24 months from manufacturing at 2–8 °C |
| Type of Usage | For Research Use Only (RUO). |
Product Properties
| Host | Mouse |
|---|---|
| Clonality | Monoclonal |
| Reactivity | |
| Conjugation | Unconjugated |
| Purification | Purity accurate to >= 95 % |
| Isotype | IgG1 |
| Formulation | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
Target
| Gene ID | |
|---|---|
| Gene Symbol | |
| Molecular Weight | 25 kDa |
| Database Links | |
| Alternative Names | C-reactive protein antibody PTX1 antibody |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine, Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells |
| Cellular Localization | Secreted |
| Tissue Specificity | Found in plasma. |
| Swiss-Prot Key |