Anti-CRTC2 Antibody

Rs. 68,577.00
SKU stj72495

General Information

Product name Anti-CRTC2 Antibody
Short Description Goat polyclonal to CRTC2
Description
Applications ELISA, WB, IHC
Dilution range
Protein Name Anti-CRTC2 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 73.3 kDa
Database Links
Alternative Names CRTC2CREB-regulated transcription coactivator 2 antibodyTransducer of regulated cAMP response element-binding protein 2 antibodyTORC-2 antibodyTransducer of CREB protein 2CRTC2 antibodyTORC2
Function Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites, Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation, Enhances the interaction of CREB1 with TAF4, Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway, Regulates the expression of specific genes such as the steroidogenic gene, StAR, Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells, Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR),
Cellular Localization Cytoplasm,
Tissue Specificity Most abundantly expressed in the thymus, present in both b and t-lymphocytes, highly expressed in hek293t cells and in insulinomas, high levels also in spleen, ovary, muscle and lung, with highest levels in muscle, lower levels found in brain, colon, heart, kidney, prostate, small intestine and stomach, weak expression in liver and pancreas,
Swiss-Prot Key

 

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