Anti-CRX Antibody

Rs. 45,619.00
SKU stj28286

General Information

Product name Anti-CRX Antibody
Short Description Rabbit polyclonal to CRX
Description The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CRX Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 120-285 of human CRX (NP_000545.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 32.3 kDa
Database Links
Alternative Names CRXCone-rod homeobox proteinCRX antibodyCORD2
Function Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes, Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription, Essential for the maintenance of mammalian photoreceptors.
Cellular Localization Nucleus
Tissue Specificity Retina
Swiss-Prot Key

 

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