Anti-CSF3R Antibody

Rs. 45,619.00
SKU stj29974

General Information

Product name Anti-CSF3R Antibody
Short Description Rabbit polyclonal to CSF3R
Description The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CSF3R Antibody
Immunogen A synthetic peptide corresponding to a sequence within amino acids 650-750 of human CSF3R (NP_000751.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 92.2 kDa
Database Links
Alternative Names CSF3RGranulocyte colony-stimulating factor receptor antibodyG-CSF receptor antibodyG-CSF-R antibodyCD antigen CD114CSF3R antibodyGCSFR
Function Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation, Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage, In addition it may function in some adhesion or recognition events at the cell surface.
Cellular Localization Secreted
Tissue Specificity One or several isoforms have been found in myelogenous leukemia cell line kg-1, leukemia u-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes, isoform gcsfr-2 is found only in leukemia u-937 cells, isoform gcsfr-3 is highly expressed in placenta
Swiss-Prot Key

 

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