Anti-CSNK1E Antibody

Rs. 45,619.00
SKU stj28096

General Information

Product name Anti-CSNK1E Antibody
Short Description Rabbit polyclonal to CSNK1E
Description The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene.
Applications WB,IHC,IF,IP
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:100
Protein Name Anti-CSNK1E Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 247-416 of human CSNK1E (NP_689407.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 47.3 kDa
Database Links
Alternative Names CSNK1ECasein kinase I isoform epsilon antibodyCKI-epsilon antibodyCKIeCSNK1E
Function Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates, Can phosphorylate a large number of proteins, Participates in Wnt signaling, Phosphorylates DVL1 and DVL2, Central component of the circadian clock, In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation, Controls PER1 and PER2 nuclear transport and degradation, Inhibits cytokine-induced granuloytic differentiation.
Cellular Localization Cytoplasm
Tissue Specificity Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle, expressed in monocytes and lymphocytes but not in granulocytes
Swiss-Prot Key

 

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