Anti-CSNK1G2 Antibody

Rs. 45,619.00
SKU stj29465

General Information

Product name Anti-CSNK1G2 Antibody
Short Description Rabbit polyclonal to CSNK1G2
Description
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-CSNK1G2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 316-415 of human CSNK1G2 (NP_001310.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 47.5 kDa
Database Links
Alternative Names CSNK1G2Casein kinase I isoform gamma-2 antibodyCKI-gamma 2CSNK1G2 antibodyCK1G2
Function Serine/threonine-protein kinase, Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates, It can phosphorylate a large number of proteins, Participates in Wnt signaling, Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3, Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles, Regulates fast synaptic transmission mediated by glutamate, SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses, Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis, Triggers PER1 proteasomal degradation probably through phosphorylation.
Cellular Localization Cytoplasm
Tissue Specificity Testis
Swiss-Prot Key

 

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