Anti-CSTA Antibody

Rs. 45,619.00
SKU stj27653

General Information

Product name Anti-CSTA Antibody
Short Description Rabbit polyclonal to CSTA
Description The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-CSTA Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-98 of human CSTA (NP_005204.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 11 kDa
Database Links
Alternative Names CSTACystatin-A antibodyCystatin-AS antibodyStefin-ACSTA antibodySTF1 antibodySTFA
Function This is an intracellular thiol proteinase inhibitor, Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis.
Cellular Localization Cytoplasm
Tissue Specificity Expressed in the skin throughout the epidermis.
Swiss-Prot Key

 

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