Anti-CTSB Antibody

Rs. 45,619.00
SKU stj23278

General Information

Product name Anti-CTSB Antibody
Short Description Rabbit polyclonal to CTSB
Description This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of this gene have been identified.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CTSB Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human CTSB (NP_001899.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 37.8 kDa
Database Links
Alternative Names CTSBCathepsin BCTSB antibodyCPSB
Function Thiol protease which is believed to participate in intracellular degradation and turnover of proteins, Has also been implicated in tumor invasion and metastasis
Cellular Localization Lysosome.
Tissue Specificity
Swiss-Prot Key

 

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