Anti-CTSK Antibody

Rs. 45,619.00
SKU stj23283

General Information

Product name Anti-CTSK Antibody
Short Description Rabbit polyclonal to CTSK
Description The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
Protein Name Anti-CTSK Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 115-329 of human CTSK (NP_000387.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 37 kDa
Database Links
Alternative Names CTSKCathepsin K CTSK antibodyCTSO antibodyCTSO2
Function Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling, Displays potent endoprotease activity against fibrinogen at acid pH, May play an important role in extracellular matrix degradation
Cellular Localization Lysosome
Tissue Specificity Predominantly expressed in osteoclasts (bones)
Swiss-Prot Key

 

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