Anti-CTTN Antibody

Rs. 45,619.00
SKU stj28359

General Information

Product name Anti-CTTN Antibody
Short Description Rabbit polyclonal to CTTN
Description This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CTTN Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 214-513 of human CTTN (NP_612632.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 61.6 kDa
Database Links
Alternative Names CTTNSrc substrate cortactin antibodyAmplaxin antibodyOncogene EMS1CTTN antibodyEMS1
Function Contributes to the organization of the actin cytoskeleton and cell shape.
Cellular Localization Cytoplasm, cytoskeleton.
Tissue Specificity
Swiss-Prot Key

 

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