Anti-CXCL8 Antibody

Rs. 45,619.00
SKU stj24194

General Information

Product name Anti-CXCL8 Antibody
Short Description Rabbit polyclonal to CXCL8
Description The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-CXCL8 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 21-99 of human IL8 (NP_000575.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 11.1 kDa
Database Links
Alternative Names CXCL8Interleukin-8 antibodyIL-8 antibodyC-X-C motif chemokine 8 antibodyChemokine antibodyC-X-C motif antibodyligand 8 antibodyEmoctakin antibodyGranulocyte chemotactic protein 1 antibodyGCP-1 antibodyMonocyte-derived neutrophil chemotactic factor antibodyMDNCF antibodyMonocyte-derived neutrophil-activating peptide antibodyMONAP antibodyNeutrophil-activating protein 1 antibodyNAP-1 antibodyProtein 3-10C antibodyT-cell chemotactic factorCXCL8 antibodyIL8
Function IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes, It is also involved in neutrophil activation, It is released from several cell types in response to an inflammatory stimulus, IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
Cellular Localization Secreted
Tissue Specificity
Swiss-Prot Key

 

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