Anti-CYB5R3 Antibody

Rs. 45,619.00
SKU stj29673

General Information

Product name Anti-CYB5R3 Antibody
Short Description Rabbit polyclonal to CYB5R3
Description This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CYB5R3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 125-334 of human CYB5R3 (NP_001165131.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 34.2 kDa
Database Links
Alternative Names CYB5R3NADH-cytochrome b5 reductase 3 antibodyB5R antibodyCytochrome b5 reductaseCYB5R3 antibodyDIA1
Function Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity Isoform 2 is expressed at late stages of erythroid maturation
Swiss-Prot Key

 

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