Anti-Cyclin A antibody

Rs. 50,211.00
SKU stj92532

General Information

Product name Anti-Cyclin A antibody
Short Description Rabbit polyclonal to Cyclin A.
Description Cyclin A is a protein encoded by the CCNA1 gene which is approximately 52,3 kDa. Cyclin A is localised to the nucleus. It is involved in CDK-mediated phosphorylation, removal of Cdc6, DNA double-strand break repair and cellular senescence. It functions as a regulator of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This protein's primarily function is in the control of the germline meiotic cell cycle. Cyclin A is very highly expressed in the testis. Mutations in the CCNA1 gene may result in myeloid leukemia. stj92532 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Cyclin A protein.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000
Protein Name Anti-Cyclin A antibody
Immunogen Synthesized peptide derived from human Cyclin A
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat,Monkey
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 53 kDa
Database Links
Alternative Names Cyclin-A1 antibody
Function May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
Cellular Localization Nucleus
Tissue Specificity Very high levels in testis and very low levels in brain. Also found in myeloid leukemia cell lines.
Swiss-Prot Key

 

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