Anti-CYP11B1 Antibody

Rs. 45,619.00
SKU stj117240

General Information

Product name Anti-CYP11B1 Antibody
Short Description Rabbit polyclonal to CYP11B1
Description This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
Applications IF
Dilution range IF 1:50 - 1:200
Protein Name Cytochrome P450 11B1mitochondrialCYPXIB1Cytochrome P-450c11Cytochrome P450C11Steroid 11-beta-hydroxylase
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP11B1 (NP_000488.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 57.6 kDa
Database Links
Alternative Names CYP11B1Cytochrome P450 11B1 antibodymitochondrial antibodyCYPXIB1 antibodyCytochrome P-450c11 antibodyCytochrome P450C11 antibodySteroid 11-beta-hydroxylaseCYP11B1 antibodyS11BH
Function Has steroid 11-beta-hydroxylase activity, In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB
Cellular Localization Mitochondrion membrane
Tissue Specificity
Swiss-Prot Key

 

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