Anti-CYP26B1 Antibody

Rs. 68,577.00
SKU stj71030

General Information

Product name Anti-CYP26B1 Antibody
Short Description Goat polyclonal to CYP26B1
Description
Applications ELISA, IHC
Dilution range
Protein Name Anti-CYP26B1 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 57.5 kDa
Database Links
Alternative Names CYP26B1Cytochrome P450 26B1 CYP26B1 antibodyCYP26A2 antibodyP450RAI2
Function Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation, Involved in the specific inactivation of all-trans-retinoic acid (all-trans-RA), with a preference for the following substrates: all-trans-RA > 9-cis-RA > 13-cis-RA, Generates several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA, and 18-OH-RA, Essential for postnatal survival, Plays a central role in germ cell development: acts by degrading RA in the developing testis, preventing STRA8 expression, thereby leading to delay of meiosis, Required for the maintenance of the undifferentiated state of male germ cells during embryonic development in Sertoli cells, inducing arrest in G0 phase of the cell cycle and preventing meiotic entry, Plays a role in skeletal development, both at the level of patterning and in the ossification of bone and the establishment of some synovial joints,
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity Highly expressed in brain, particularly in the cerebellum and pons,
Swiss-Prot Key

 

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