Anti-CYP2C9 Antibody

Rs. 45,619.00
SKU stj27975

General Information

Product name Anti-CYP2C9 Antibody
Short Description Rabbit polyclonal to CYP2C9
Description This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:10 - 1:100
Protein Name Anti-CYP2C9 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 211-490 of human CYP2C9 (NP_000762.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 55.6 kDa
Database Links
Alternative Names CYP2C9Cytochrome P450 2C9 CYP2C9 antibodyCYP2C10
Function Cytochromes P450 are a group of heme-thiolate monooxygenases, In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway, It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity
Swiss-Prot Key

 

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