Anti-CYP2J2 Antibody

Rs. 45,619.00
SKU stj28368

General Information

Product name Anti-CYP2J2 Antibody
Short Description Rabbit polyclonal to CYP2J2
Description This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. Multiple transcript variants have been found for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CYP2J2 Antibody
Immunogen A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CYP2J2 (NP_000766.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 57.6 kDa
Database Links
Alternative Names CYP2J2Cytochrome P450 2J2 CYP2J2
Function This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids, One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney
Swiss-Prot Key

 

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