Anti-CYP3A4 antibody

Rs. 50,211.00
SKU stj92593

General Information

Product name Anti-CYP3A4 antibody
Short Description
Description Rabbit polyclonal to CYP3A4.
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000
Protein Name Anti-CYP3A4 antibody
Immunogen Synthesized peptide derived from human CYP3A4
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 57 kDa
Database Links
Alternative Names Cytochrome P450 3A4 antibody
1,8-cineole 2-exo-monooxygenase antibody
Albendazole monooxygenase antibody
Albendazole sulfoxidase antibody
CYPIIIA3 antibody
CYPIIIA4 antibody
Cholesterol 25-hydroxylase antibody
Cytochrome P450 3A3 antibody
Cytochrome P450 HLp antibody
Cytochrome P450 NF-25 antibody
Cytochrome P450-PCN1 antibody
Nifedipine oxidase antibody
Quinine 3-monooxygenase antibody
Taurochenodeoxycholate 6-alpha-hydroxylase antibody
CYP3A3 antibody
Function Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide . Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro .
Cellular Localization Endoplasmic reticulum membrane. Single-pass membrane protein. Microsome membrane {ECO:0000269|PubMed:21576599}. Single-pass membrane protein.
Tissue Specificity Expressed in prostate and liver. According to some authors, it is not expressed in brain . According to others, weak levels of expression are measured in some brain locations . Also expressed in epithelium of the small intestine and large intestine, bile duct, nasal mucosa, kidney, adrenal cortex, epithelium of the gastric mucosa with intestinal metaplasia, gallbladder, intercalated ducts of the pancreas, chief cells of the parathyroid and the corpus luteum of the ovary (at protein level).
Swiss-Prot Key

 

You recently viewed

Clear recently viewed