Anti-CYP3A5 Antibody

Rs. 61,689.00
SKU stj23327

General Information

Product name Anti-CYP3A5 Antibody
Short Description Rabbit polyclonal to CYP3A5
Description This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:50
Protein Name Anti-CYP3A5 Antibody
Immunogen A synthetic peptide of human CYP3A5
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 57.1 kDa
Database Links
Alternative Names CYP3A5Cytochrome P450 3A5 CYP3A5
Function Cytochromes P450 are a group of heme-thiolate monooxygenases, In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway, It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity
Swiss-Prot Key

 

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