Anti-CysLTR1 antibody

Rs. 50,211.00
SKU stj92609

General Information

Product name Anti-CysLTR1 antibody
Short Description
Description Rabbit polyclonal to CysLTR1.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000
Protein Name Anti-CysLTR1 antibody
Immunogen Synthesized peptide derived from human CysLTR1
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Monkey
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 36 kDa
Database Links
Alternative Names Cysteinyl leukotriene receptor 1 antibody
Cysteinyl leukotriene D4 receptor antibody
LTD4 receptor antibody
G-protein coupled receptor HG55 antibody
HMTMF81 antibody
CYSLT1 antibody
Function Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Cellular Localization Cell membrane. Multi-pass membrane protein.
Tissue Specificity Widely expressed, with highest levels in spleen and peripheral blood leukocytes. Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart.
Swiss-Prot Key

 

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