Anti-DAP3 Antibody

Rs. 45,619.00
SKU stj29083

General Information

Product name Anti-DAP3 Antibody
Short Description Rabbit polyclonal to DAP3
Description Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-DAP3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 159-398 of human DAP3 (NP_387506.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 45.6 kDa
Database Links
Alternative Names DAP328S ribosomal protein S29 antibodymitochondrial antibodyMRP-S29 antibodyS29mt antibodyDeath-associated protein 3 antibodyDAP-3 antibodyIonizing radiation resistance conferring protein antibodyMitochondrial small ribosomal subunit protein mS29DAP3 antibodyMRPS29
Function Involved in mediating interferon-gamma-induced cell death
Cellular Localization Mitochondrion
Tissue Specificity Ubiquitous
Swiss-Prot Key

 

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