Anti-DAZ2 Antibody

Rs. 45,619.00
SKU stj29737

General Information

Product name Anti-DAZ2 Antibody
Short Description Rabbit polyclonal to DAZ2
Description This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-DAZ2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DAZ2 (NP_001005785.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 63.1 kDa
Database Links
Alternative Names DAZ2Deleted in azoospermia protein 2DAZ2
Function RNA-binding protein that plays an essential role in spermatogenesis, May act by binding to the 3'-UTR of mRNAs and regulating their translation
Cellular Localization Cytoplasm.
Tissue Specificity Testis specific.
Swiss-Prot Key

 

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