Anti-DBN1 Antibody

Rs. 45,619.00
SKU stj28449

General Information

Product name Anti-DBN1 Antibody
Short Description Rabbit polyclonal to DBN1
Description The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name Anti-DBN1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 350-649 of human DBN1 (NP_004386.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 71.4 kDa
Database Links
Alternative Names DBN1Drebrin antibodyDevelopmentally-regulated brain proteinDBN1 antibodyD0S117E
Function Drebrins might play some role in cell migration, extension of neuronal processes and plasticity of dendrites, Required for actin polymerization at immunological synapses (IS) and for CXCR4 recruitment to IS.
Cellular Localization Cytoplasm.
Tissue Specificity Brain neurons, also found in the heart, placenta, skeletal muscle, kidney and pancreas, expressed in peripheral blood lymphocytes, including t-cells (at protein level).
Swiss-Prot Key

 

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