Anti-DCAF7 Antibody

Rs. 45,619.00
SKU stj28870

General Information

Product name Anti-DCAF7 Antibody
Short Description Rabbit polyclonal to DCAF7
Description This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:10 - 1:100
Protein Name Anti-DCAF7 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human DCAF7 (NP_005819.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 38.9 kDa
Database Links
Alternative Names DCAF7DDB1- and CUL4-associated factor 7 antibodyWD repeat-containing protein 68 antibodyWD repeat-containing protein An11 homologDCAF7 antibodyHAN11 antibodyWDR68
Function Involved in craniofacial development, Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate, The activity required for EDN1 pathway function differs between the first and second arches (By similarity), Associates with DIAPH1 and controls GLI1 transcriptional activity, Could be involved in normal and disease skin development, May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Cellular Localization Cytoplasm, Nucleus.
Tissue Specificity
Swiss-Prot Key

 

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