Anti-DCP1A Antibody

Rs. 45,619.00
SKU stj29513

General Information

Product name Anti-DCP1A Antibody
Short Description Rabbit polyclonal to DCP1A
Description Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants.
Applications IF
Dilution range IF 1:20 - 1:50
Protein Name Anti-DCP1A Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 303-582 of human DCP1A (NP_060873.4).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 63.3 kDa
Database Links
Alternative Names DCP1AmRNA-decapping enzyme 1A DCP1A antibodySMIF
Function Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay, Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP, Contributes to the transactivation of target genes after stimulation by TGFB1.
Cellular Localization Cytoplasm, P-body.
Tissue Specificity Detected in heart, brain, placenta, lung, skeletal muscle, liver, kidney and pancreas.
Swiss-Prot Key

 

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