Anti-DCX Antibody

Rs. 68,577.00
SKU stj72521

General Information

Product name Anti-DCX Antibody
Short Description Goat polyclonal to DCX
Description
Applications ELISA, WB, IHC, IF
Dilution range
Protein Name Anti-DCX Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 40.6 kDa
Database Links
Alternative Names DCXNeuronal migration protein doublecortin antibodyDoublin antibodyLissencephalin-X antibodyLis-XDCX antibodyDBCN antibodyLISX
Function Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development, May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein, May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway, May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration,
Cellular Localization Cytoplasm
Tissue Specificity Highly expressed in neuronal cells of fetal brain (in the majority of cells of the cortical plate, intermediate zone and ventricular zone), but not expressed in other fetal tissues, in the adult, highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas
Swiss-Prot Key

 

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