Anti-DEFA3 Antibody

Rs. 45,619.00
SKU stj27293

General Information

Product name Anti-DEFA3 Antibody
Short Description Rabbit polyclonal to DEFA3
Description Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-DEFA3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 20-94 of human DEFA3 (NP_005208.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 10.2 kDa
Database Links
Alternative Names DEFA3Neutrophil defensin 3 antibodyDefensin antibodyalpha 3 antibodyHNP-3 antibodyHP-3 antibodyHP3DEFA3 antibodyDEF3
Function Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities, Has antimicrobial activity against Gram-negative and Gram-positive bacteria, Defensins are thought to kill microbes by permeabilizing their plasma membrane.
Cellular Localization Secreted
Tissue Specificity
Swiss-Prot Key

 

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