Anti-DGAT1 Antibody

Rs. 45,619.00
SKU stj28938

General Information

Product name Anti-DGAT1 Antibody
Short Description Rabbit polyclonal to DGAT1
Description This gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
Protein Name Anti-DGAT1 Antibody
Immunogen A synthetic peptide corresponding to a sequence within amino acids 200-300 of human DGAT1 (NP_036211.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 55.3 kDa
Database Links
Alternative Names DGAT1Diacylglycerol O-acyltransferase 1 DGAT1 antibodyAGRP1 antibodyDGAT
Function Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates, In contrast to DGAT2 it is not essential for survival, May be involved in VLDL (very low density lipoprotein) assembly, In liver, plays a role in esterifying exogenous fatty acids to glycerol, Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity
Swiss-Prot Key

 

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