Anti-DGCR8 Antibody

Rs. 57,098.00
SKU stj71824

General Information

Product name Anti-DGCR8 Antibody
Short Description Goat polyclonal to DGCR8
Description
Applications ELISA
Dilution range
Protein Name Anti-DGCR8 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 86 kDa
Database Links
Alternative Names DGCR8Microprocessor complex subunit DGCR8 antibodyDiGeorge syndrome critical region 8DGCR8 antibodyC22orf12 antibodyDGCRK6 antibodyLP4941
Function Component of the microprocessor complex that acts as a RNA- and heme-binding protein that is involved in the initial step of microRNA (miRNA) biogenesis, Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus, Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs ,
Cellular Localization Nucleus,
Tissue Specificity Ubiquitously expressed,
Swiss-Prot Key

 

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