Anti-DGK-θ antibody

Rs. 50,211.00
SKU stj92702

General Information

Product name Anti-DGK-θ antibody
Short Description
Description Rabbit polyclonal to DGK-θ.
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000
Protein Name Anti-DGK-θ antibody
Immunogen Synthesized peptide derived from human DGK-θ
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 101 kDa
Database Links
Alternative Names Diacylglycerol kinase theta antibody
DAG kinase theta antibody
Diglyceride kinase theta antibody
DGK-theta antibody
DAGK4 antibody
Function Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor . May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity.
Cellular Localization Cytoplasm Cell membrane Cytoplasm, cytoskeleton Nucleus Nucleus speckle. Translocates to the nucleus in response to thrombin stimulation . Translocates to the plasma membrane in response to steroid hormone receptor stimulation . Translocation to the plasma membrane is dependent on G-protein coupled receptor stimulation and subsequent activation of PRKCE and probably PRKCH .
Tissue Specificity
Swiss-Prot Key

 

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