Anti-DIAPH1 Antibody

Rs. 68,577.00
SKU stj71749

General Information

Product name Anti-DIAPH1 Antibody
Short Description Goat polyclonal to DIAPH1
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-DIAPH1 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 141.3 kDa
Database Links
Alternative Names DIAPH1Protein diaphanous homolog 1 antibodyDiaphanous-related formin-1 antibodyDRF1DIAPH1 antibodyDIAP1
Function Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers (By similarity), Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization (By similarity), Required for cytokinesis, and transcriptional activation of the serum response factor (By similarity), DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity), Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and promote cell migration (By similarity), Has neurite outgrowth promoting activity, Acts in a Rho-dependent manner to recruit PFY1 to the membrane (By similarity), In hear cells, it may play a role in the regulation of actin polymerization in hair cells ,
Cellular Localization Cell membrane
Tissue Specificity Expressed in brain, heart, placenta, lung, kidney, pancreas, liver, skeletal muscle and cochlea, expressed in platelets ,
Swiss-Prot Key

 

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