Anti-Dishevelled1 Antibody

Rs. 68,577.00
SKU stj73331

General Information

Product name Anti-Dishevelled1 Antibody
Short Description Goat polyclonal to Dishevelled1 (aa20-32)
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-Dishevelled1 Antibody
Immunogen N Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 75.4 kDa
Database Links
Alternative Names Anti-Dishevelled1 (aa20-32) Antibody
Function Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors, Plays a role both in canonical and non-canonical Wnt signaling, Plays a role in the signal transduction pathways mediated by multiple Wnt genes, Required for LEF1 activation upon WNT1 and WNT3A signaling, DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ),
Cellular Localization Cell membrane,
Tissue Specificity High levels are seen in the brain, testis and kidney, lower levels in the ovary, breast, muscle, liver and small intestine, and very low levels are seen in the spleen and thymus, a moderate level expression is seen in the heart
Swiss-Prot Key

 

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