Anti-DLC-1 antibody

Rs. 50,211.00
SKU stj92721

General Information

Product name Anti-DLC-1 antibody
Short Description
Description Rabbit polyclonal to DLC-1.
Applications IHC,IF,ELISA
Dilution range IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000
Protein Name Anti-DLC-1 antibody
Immunogen Synthesized peptide derived from human DLC-1
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 122.827 kDa
Database Links
Alternative Names Rho GTPase-activating protein 7 antibody
Deleted in liver cancer 1 protein antibody
HP protein antibody
Rho-type GTPase-activating protein 7 antibody
START domain-containing protein 12 antibody
StARD12 antibody
StAR-related lipid transfer protein 12 antibody
ARHGAP7 antibody
KIAA1723 antibody
STARD12 antibody
Function Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
Cellular Localization Cytoplasm. Cell junction, focal adhesion. Membrane. Peripheral membrane protein. Colocalizes with EF1A1 at actin-rich regions in the cell periphery.
Tissue Specificity Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.
Swiss-Prot Key

 

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