Anti-DOC-1R antibody

Rs. 50,211.00
SKU stj92755

General Information

Product name Anti-DOC-1R antibody
Short Description
Description Rabbit polyclonal to DOC-1R.
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:5000
Protein Name Anti-DOC-1R antibody
Immunogen Synthesized peptide derived from human DOC-1R
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 13.101 kDa
Database Links
Alternative Names Cyclin-dependent kinase 2-associated protein 2 antibody
CDK2-associated protein 2 antibody
DOC-1-related protein antibody
DOC1R antibody
Function Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes . Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A .
Cellular Localization Cytoplasm Nucleus. Accumulates in immature oocytes in the nucleus. During the first meiotic division, accumulates in the cytoplasm and localizes in dots in the vicinity of the chromosomes in a region enriched in microtubules.
Tissue Specificity Ubiquitous.
Swiss-Prot Key

 

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