Anti-Dok-1 antibody

Rs. 50,211.00
SKU stj92758

General Information

Product name Anti-Dok-1 antibody
Short Description
Description Rabbit polyclonal to Dok-1.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000
Protein Name Anti-Dok-1 antibody
Immunogen Synthesized peptide derived from human Dok-1 around the non-phosphorylation site of Y362.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 52 kDa
Database Links
Alternative Names Docking protein 1 antibody
Downstream of tyrosine kinase 1 antibody
p62 antibody
dok antibody
pp62 antibody
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Cellular Localization Isoform 1: Cytoplasm. Nucleus.. Isoform 3: Cytoplasm, perinuclear region.
Tissue Specificity Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells. Expressed in breast cancer.
Swiss-Prot Key

 

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