Anti-DROSHA Antibody

Rs. 68,577.00
SKU stj71047

General Information

Product name Anti-DROSHA Antibody
Short Description Goat polyclonal to DROSHA
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-DROSHA Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 159.3 kDa
Database Links
Alternative Names DROSHARibonuclease 3 DROSHA antibodyRN3 antibodyRNASE3L antibodyRNASEN
Function Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis, Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus, Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs, Involved also in pre-rRNA processing, Cleaves double-strand RNA and does not cleave single-strand RNA, Involved in the formation of GW bodies,
Cellular Localization Nucleus,
Tissue Specificity Ubiquitous,
Swiss-Prot Key

 

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