Anti-DSP Antibody

Rs. 45,619.00
SKU stj29950

General Information

Product name Anti-DSP Antibody
Short Description Rabbit polyclonal to DSP
Description This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-DSP Antibody
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DSP (NP_004406.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 331.8 kDa
Database Links
Alternative Names DSPDesmoplakin antibodyDP antibody250/210 kDa paraneoplastic pemphigus antigenDSP
Function Major high molecular weight protein of desmosomes, Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes
Cellular Localization Cell junction, desmosome.
Tissue Specificity Isoform dpi is apparently an obligate constituent of all desmosomes, isoform dpii resides predominantly in tissues and cells of stratified origin
Swiss-Prot Key

 

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