Anti-DVL2 Antibody

Rs. 45,619.00
SKU stj29689

General Information

Product name Anti-DVL2 Antibody
Short Description Rabbit polyclonal to DVL2
Description This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-DVL2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human DVL2 (NP_004413.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 78.9 kDa
Database Links
Alternative Names DVL2Segment polarity protein dishevelled homolog DVL-2 antibodyDishevelled-2 antibodyDSH homolog 2DVL2
Function Plays a role in the signal transduction pathways mediated by multiple Wnt genes, Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors, Promotes internalization and degradation of frizzled proteins upon Wnt signaling.
Cellular Localization Cell membrane.
Tissue Specificity
Swiss-Prot Key

 

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