Anti-DYNC2LI1 Antibody

Rs. 45,619.00
SKU stj26842

General Information

Product name Anti-DYNC2LI1 Antibody
Short Description Rabbit polyclonal to DYNC2LI1
Description This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-DYNC2LI1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-352 of human DYNC2LI1 (NP_001180393.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 39.6 kDa
Database Links
Alternative Names DYNC2LI1Cytoplasmic dynein 2 light intermediate chain 1 antibodyDynein 2 light intermediate chainDYNC2LI1 antibodyD2LIC antibodyLIC3 antibodyCGI-60
Function Required for correct intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia, Involved in the regulation of ciliary length.
Cellular Localization Cytoplasm
Tissue Specificity Expressed in bone, brain, kidney, and cartilage.
Swiss-Prot Key

 

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