General Information
| Product name | Anti-DYSF Antibody |
|---|---|
| Short Description | Goat polyclonal to DYSF |
| Description | |
| Applications | ELISA |
| Dilution range | |
| Protein Name | Anti-DYSF Antibody |
| Immunogen | internal region |
| Storage Instruction | |
| Type of Usage | For Research Use Only (RUO). |
Product Properties
| Host | Goat |
|---|---|
| Clonality | Polyclonal |
| Reactivity | |
| Conjugation | Unconjugated |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Isotype | |
| Formulation | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Target
| Gene ID | |
|---|---|
| Gene Symbol | |
| Molecular Weight | 237.3 kDa |
| Database Links | |
| Alternative Names | DYSFDysferlin antibodyDystrophy-associated fer-1-like protein antibodyFer-1-like protein 1DYSF antibodyFER1L1 |
| Function | Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion, Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity), |
| Cellular Localization | Cell membrane, sarcolemma |
| Tissue Specificity | Expressed in skeletal muscle, myoblast, myotube and in the syncytiotrophoblast (stb) of the placenta (at protein level), ubiquitous, highly expressed in skeletal muscle, also found in heart, brain, spleen, intestine, placenta and at lower levels in liver, lung, kidney and pancreas, |
| Swiss-Prot Key |