Anti-E2F1 Antibody

Rs. 68,577.00
SKU stj73044

General Information

Product name Anti-E2F1 Antibody
Short Description Goat polyclonal to E2F1
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-E2F1 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 46.9 kDa
Database Links
Alternative Names E2F1Transcription factor E2F1 antibodyE2F-1 antibodyPBR3 antibodyRetinoblastoma-associated protein 1 antibodyRBAP-1 antibodyRetinoblastoma-binding protein 3 antibodyRBBP-3 antibodypRB-binding protein E2F-1E2F1 antibodyRBBP3
Function Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication, The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase, E2F1 binds preferentially RB1 in a cell-cycle dependent manner, It can mediate both cell proliferation and TP53/p53-dependent apoptosis, Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters ,
Cellular Localization Nucleus
Tissue Specificity
Swiss-Prot Key

 

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