Anti-Eat2A Antibody

Rs. 57,098.00
SKU stj70937

General Information

Product name Anti-Eat2A Antibody
Short Description Goat polyclonal to Eat2A / Eat2B (mouse)
Description
Applications ELISA
Dilution range
Protein Name Anti-Eat2A Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 15.3 kDa
Database Links
Alternative Names Anti-Eat2A / Eat2B (mouse) Antibody
Function Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as CD84, SLAMF1, LY9 and CD244, In SLAM signaling seems to cooperate with SH2D1A/SAP, Plays a role in regulation of effector functions of natural killer (NK) cells by controlling signal transduction through CD244/2B4, However, conflicting results are reported which may reflect the use of different strain backgrounds, Proposed to act as an inhibitor of CD244-mediated NK cell function including cytotoxicity and IFN-gamma production, the latter found also by triggering KLRA4 and KLRK1 next to CD244 ,
Cellular Localization
Tissue Specificity Expressed in spleen, thymus, lung, kidney, heart, colon and small bowel, expressed in nk cells (all stages of cell maturation), macrophages and dendritic cells,
Swiss-Prot Key

 

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