Anti-EDG-8 antibody

Rs. 50,211.00
SKU stj92837

General Information

Product name Anti-EDG-8 antibody
Short Description
Description Rabbit polyclonal to EDG-8.
Applications IHC,IF,ELISA
Dilution range IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000
Protein Name Anti-EDG-8 antibody
Immunogen Synthesized peptide derived from human EDG-8
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 41.775 kDa
Database Links
Alternative Names Sphingosine 1-phosphate receptor 5 antibody
S1P receptor 5 antibody
S1P5 antibody
Endothelial differentiation G-protein-coupled receptor 8 antibody
Sphingosine 1-phosphate receptor Edg-8 antibody
S1P receptor Edg-8 antibody
EDG8 antibody
Function Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins . May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
Cellular Localization Cell membrane. Multi-pass membrane protein.
Tissue Specificity Widely expressed in the brain, most prominently in the corpus callosum, which is predominantly white matter. Detected in spleen, peripheral blood leukocytes, placenta, lung, aorta and fetal spleen. Low-level signal detected in many tissue extracts. Overexpressed in leukemic large granular lymphocytes. Isoform 1 is predominantly expressed in peripheral tissues. Isoform 2 is expressed in brain, spleen and peripheral blood leukocytes.
Swiss-Prot Key

 

You recently viewed

Clear recently viewed