Anti-EEF2K Antibody

Rs. 45,619.00
SKU stj27357

General Information

Product name Anti-EEF2K Antibody
Short Description Rabbit polyclonal to EEF2K
Description This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Anti-EEF2K Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 406-725 of human EEF2K (NP_037434.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 82.1 kDa
Database Links
Alternative Names EEF2KEukaryotic elongation factor 2 kinase antibodyeEF-2 kinase antibodyeEF-2KEEF2K
Function Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation, Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive, In turn, the rate of protein synthesis is reduced.
Cellular Localization
Tissue Specificity
Swiss-Prot Key

 

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